So many experts have done a lot of research on the toxicity of 1,2,4-TCB, with the advancement of the research on ROS and diseases, demonstrating that free radical is closely relevant to various toxin injury. 国内外许多学者对1,2,4&TCB的毒性已经作了大量研究,随着活性氧自由基与疾病研究的进展,揭示出自由基与多种毒物损伤存在着密切关系。
[ Conclusions] In the course of acute brain ischemia injury the important cascade reaction, including disturbance of energy metabolism, acidosis and free radical injury has provided the pathologic and physiologic foundation for the mechanism study of toxin damaging brain collaterals. [结论]在急性脑缺血损伤过程中,能量代谢障碍、酸中毒、自由基损伤等级联反应重要环节,为毒损脑络机制提供了病生理学依据。
Foreign studies showed that chitosan can regulate cell differentiation, proliferation and cytokine production, scavenging free radicals, and the toxin in the body, protecting the brain nerve cells and glial cell membrane. 国外研究表明,壳聚糖能调节细胞分化、增殖及细胞因子的产生,清除自由基,中和体内毒素,保护脑神经细胞和神经胶质细胞膜。